Best Gemini prompts for Genetic Counselors

Given a dataset of 1000 genomic variants from a recent exome sequencing project, use Google BigQuery to filter variants with a minor allele frequency less than 0.01 and then apply the ACMG guidelines to classify these variants as pathogenic, likely pathogenic, uncertain significance, likely benign, or benign, considering the clinical context of a patient with a family history of breast cancer, and output the results in a tabular format suitable for import into our electronic health record system, including recommendations for follow-up testing or genetic counseling based on the classification.

Create a detailed pedigree chart for a family with a history of cystic fibrosis, incorporating genetic testing results from our laboratory information system, and identify all at-risk relatives who should be offered genetic counseling and testing, considering the mode of inheritance and penetrance of the disorder, and then use Google Sheets to calculate the probability of each relative being a carrier of the mutated gene, assuming a carrier frequency of 1 in 25 in the general population.

Interpret the results of a genetic testing report for a patient who underwent panel testing for hereditary cancer syndromes, using our internal database of gene-disease associations to identify any pathogenic or likely pathogenic variants, and then generate a clinical summary report in a format compatible with our genetic counseling software, including recommendations for surveillance, screening, and risk-reducing interventions based on the patient's genetic profile and family history.

Design a recruitment protocol for a research study investigating the genetic basis of a rare inherited disorder, using our institution's patient registry and Google Data Studio to identify potentially eligible participants based on their diagnosis, genetic testing results, and demographic characteristics, and then develop an informed consent document and a plan for disclosing genetic results to participants, ensuring compliance with IRB regulations and our institutional policies for human subjects research.